The Onset of Action of Cetirizine Compared to Antihistamines in Allergic Rhinitis. March 2022.
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References
Banerji A, Long AA, Camargo CA. Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review. Allergy Asthma Proc. 2007;28(4):418-26.
Chipps BE, Harder JM. Antihistamine treatment for allergic rhinitis: different routes, different outcomes?. Allergy Asthma Proc. 2009;30(6):589-94.
Corren J, Storms W, Bernstein J, Berger W, Nayak A, Sacks H, No TA, Group S. Effectiveness of azelastine nasal spray compared with oral cetirizine in patients with seasonal allergic rhinitis. Clinical therapeutics. 2005 May 1;27(5):543-53.
Day JH, Briscoe M, Rafeiro E, Chapman D, Kramer B. Comparative onset of action and symptom relief with cetirizine, loratadine, or placebo in an environmental exposure unit in subjects with seasonal allergic rhinitis: confirmation of a test system. Ann Allergy Asthma Immunol. 2001;87(6):474-81.
Day JH, Briscoe M, Widlitz MD. Cetirizine, loratadine, or placebo in subjects with seasonal allergic rhinitis: Effects after controlled ragweed pollen challenge in an environmental exposure unit. J Allergy Clin Immunol. 1998; 101:638-45.
Day JH, Briscoe MP, Clark RH, Ellis AK, Gervais P. Onset of action and efficacy of terfenadine, astemizole, cetirizine, and loratadine for the relief of symptoms of allergic rhinitis. Ann Allergy Asthma Immunol 1997;79:163–72.
Del cuvillo A, Mullol J, Bartra J, et al. Comparative pharmacology of the H1 antihistamines. J Investig Allergol Clin Immunol. 2006;16 Suppl 1:3-12.
Drouin MA, Yang WH, Horak F. Faster onset of action with topical levocabastine than with oral cetirizine. Mediators Inflamm. 1995;4(7):S5-S10.
Ellis AK, Zhu Y, Steacy LM, Walker T, Day JH. A four-way, double-blind, randomized, placebo controlled study to determine the efficacy and speed of azelastine nasal spray, versus loratadine, and cetirizine in adult subjects with allergen-induced seasonal allergic rhinitis. Allergy Asthma Clin Immunol. 2013;9(1):16.
Fitzsimons R, Van der poel LA, Thornhill W, Du toit G, Shah N, Brough HA. Antihistamine use in children. Arch Dis Child Educ Pract Ed. 2015;100(3):122-31.
Frossard N, Benabdesselam O, Melac M, Glasser N, Lacronique J, Pauli G. Nasal effect of cetirizine and loratadine at 24 hours in patients with allergic rhinitis. Am J Ther. 1998;5(5):307-11.
Frossard N, Lacronique J, Melac M, et al. Onset of action in the nasal antihistaminic effect of cetirizine and loratadine in patients with allergic rhinitis. Allergy. 1997;52(2):205-9.
Galant SP, Wilkinson R. Clinical prescribing of allergic rhinitis medication in the preschool and young school-age child: what are the options. BioDrugs. 2001;15(7):453-63.
Greisner WA. Onset of action for the relief of allergic rhinitis symptoms with second-generation antihistamines. Allergy Asthma Proc. 2004;25(2):81-3.
Horak F, Stuebner P, Zieglmayer R, et al. Controlled comparison of the efficacy and safety of cetirizine 10 mg o.d. and fexofenadine 120 mg o.d. in reducing symptoms of seasonal allergic rhinitis. Int.Arch.Allergy Immunol. 2001; 125(1):73-79.
Horak F, Zieglmayer P, Zieglmayer R, Lemell P. The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen- induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna challenge chamber. 2010; 59(5):391
Horak F, Zieglmayer UP. Azelastine nasal spray for the treatment of allergic and nonallergic rhinitis. Expert Rev Clin Immunol. 2009;5(6):659-69.
Horak F. Effectiveness of twice daily azelastine nasal spray in patients with seasonal allergic rhinitis. Ther Clin Risk Manag. 2008;4(5):1009-22.
Hyo S, Fujieda S, Kawada R, Kitazawa S, Takenaka H. The efficacy of short-term administration of 3 antihistamines vs. placebo under natural exposure to Japanese cedar pollen. Ann.Allergy Asthma Immunol. 2005; 94(4):257-64.
ISAAC. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Lancet 1998 Apr 25; 351 (9111): 1225-32
Kaliner MA. A novel and effective approach to treating rhinitis with nasal antihistamines. Ann Allergy Asthma Immunol. 2007;99(5):383-90.
Kapoor Y, Kumar K. Structural and clinical impact of anti-allergy agents: An overview. Bioorg Chem. 2020;94. https://dialog.proquest.com/professional/docview/2313748567?accountid=190963. doi: http://dx.doi.org/10.1016/j.bioorg.2019.103351.
Kunkel G. Treatment of allergic rhinoconjunctivitis: topical and/or systemic administration?. Allergologie. 1998; 21(4):S37-S45.
Lehman JM, Blaiss MS. Selecting the optimal oral antihistamine for patients with allergic rhinitis. Drugs. 2006;66(18):2309-19.
Mcneely W, Wiseman LR. Intranasal azelastine. A review of its efficacy in the management of allergic rhinitis. Drugs. 1998;56(1):91-114.
Meltzer EO, Waller JM, Widlitz MD. Comparative outdoor study of the efficacy, onset and duration of action, and safety of cetirizine, Ioratadine, and placebo for seasonal allergic rhinitis. J Allergy Clin Immunol. 1996; 97(2):617-626.
Meltzer EO. Evaluation of the optimal oral antihistamine for patients with allergic rhinitis. Mayo Clin Proc. 2005;80(9):1170-6.
Mittal, Pranjal Anil, Kiran V. Godse, and Sharmila P. Patil. "Second-generation antihistamines." Indian Journal of Drugs in Dermatology. 2016: 3.
Nielsen LP, Mygind N, Dahl R. Intranasal corticosteroids for allergic rhinitis: superior relief?. Drugs. 2001;61(11):1563-79.
Prenner BM. Comparative efficacy of antihistamines in Allergic Rhinitis and Urticaria. Clinical and Applied Immunology Reviews. 2001;1(3-4):217-24.
Ratz JD, Day JH, Briscoe MP. A Placebo-Controlled, Four-Way Crossover Study Comparing Azelastine Nasal Spray, Cetirizine and Loratadine in Adult Subjects with Ragweed-Induced Seasonal Allergic Rhinitis in the Environmental Exposure Unit (EEU). J Allergy Clin Immunol. 2009; 123(2):Abs491
Scadding GK. Clinical assessment of antihistamines in rhinitis. Clin Exp Allergy. 1999;29 Suppl 3:77-81.
Sienra-monge JJ, Gazca-aguilar A, Del rio-navarro B. Double-blind comparison of cetirizine and loratadine in children ages 2 to 6 years with perennial allergic rhinitis. Am J Ther. 1999;6(3):149-55.
Simons FE, Simons KJ. H1 antihistamines: current status and future directions. World Allergy Organ J. 2008;1(9):145-55.
Simons FE, Simons KJ. Histamine and H1-antihistamines: celebrating a century of progress. J Allergy Clin Immunol. 2011;128(6):1139-1150.e4.
Tenn MW, Steacy LM, Ng CC, Ellis AK. Onset of action for loratadine tablets for the symptomatic control of seasonal allergic rhinitis in adults challenged with ragweed pollen in the Environmental Exposure Unit: a post hoc analysis of total symptom score. Allergy, Asthma & Clinical Immunology. 2018;14(1). doi:10.1186/s13223-017-0227-4.
Tillement JP, Testa B, Brée F. Compared pharmacological characteristics in humans of racemic cetirizine and levocetirizine, two histamine H1-receptor antagonists. Biochem Pharmacol. 2003;66(7):1123-6.